Roxithromycin prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.
Do not use this medication if you are alleric to Clarithromycin - Generic Rulide or to similar medicines such as azithromycin (Zithromax), dirithromycin (Dynabac), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), roxithromycin (Rulid, Surlid), or telithromycin (Ketek). Do not use Clarithromycin - Generic Rulide if you are also using any of the drugs listed below. Roxithromycin is a semi-synthetic macrolide antibiotic. It is used
to treat respiratory tract, urinary and soft tissue infections.
Roxithromycin is derived from erythromycin, containing the same
14-membered lactone ring. However, an N-oxime side chain is attached
to the lactone ring. It is also currently undergoing clinical trials
for the treatment of male-pattern hair loss. Roxithromycin is available
under several brandnames, for example Surlid, Rulide, Biaxsig, Roxar
and Roximycin. Roxithromycin is not available in the United States.
Roxithromycin has also been tested to possess antimalarial activity.
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Most common side effects are gastrointestinal; diarrhoea, nausea, abdominal pain and vomiting. Less common side effects include central or peripheral nervous system events such as headaches, dizziness, vertigo, and also the rarely seen rashes, abnormal liver function values and alteration in senses of smell and taste.
Seek emergency medical attention if you think you have used too much of this medicine.
Symptoms of a Clarithromycin - Generic Rulide overdose may include nausea, vomiting, diarrhea, and abdominal discomfort.
What should I avoid while taking Clarithromycin - Generic Rulide?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.